Molecure invites to the R&D Day – an online scientific and educational meeting on February 6, 2024
Warsaw, Poland – 29th January 2024 – Molecure S.A. (WSE ticker: MOC) a biotechnology company discovering and developing drugs to the clinical stage, utilizes world-class expertise in medicinal chemistry and biology to search for and develop first-in-class small molecule drugs that directly modulate the activity of proteins and mRNA functions in the therapy of various incurable diseases, presents the agenda for the Molecure R&D Day online meeting and introduces profiles of external experts (Key Opinion Leaders). The invited experts will discuss topics related to methods used to study RNA structure and interaction with small-molecule ligands during the meeting.
The Molecure R&D Day online is scheduled for February 6, 2024 (Tuesday), 13:00-15:30 CET.
Link to registration (option to submit written questions):
in English: https://livingmedia.com.pl/live/molecure/RD-Day-en
in Polish: https://livingmedia.com.pl/live/molecure/RD-Day-pl
Presentation: R&D Day 6.02.2024
The meeting will be conducted primarily in English, as well as in Polish (simultaneous translation to Polish will be provided), with the option to ask questions in both Polish and English.
The Molecure managers will discuss the progress of clinical programs and provide an overview of the deubiquitinase platform and mRNA platform. Additionally, invited external experts (Key Opinion Leaders) will present selected aspects related to methods used for studying RNA structure and interaction with small-molecule ligands
Agenda:
13:00-15:00
- Development plans in 2024
- OATD-01 i OATD-02 programs – 2024 a year of clinical studies
- DUBs program – deubiquitinase as a significant group of therapeutic targets in oncology
- Future of mRNA platform
- “MoleCuring” – treatment of diseases through the utilization of mRNA targeting mechanisms – methods for the identification of compounds – Joanna Sztuba-Solińska, PhD
- Study of RNA structure using methods such as DyRNA Thermometry and cryo-electron microscopy (cryo-EM) – Jakub Nowak, PhD
15:00-15:30
- Q&A session
External experts (Key Opinion Leaders):
- Joanna Sztuba-Solińska, PhD
An eminent specialist in the field of RNA recombination mechanisms, for many years she has been conducting research on the structure and function of coding and non-coding RNA. She has been affiliated with various institutions, including the National Institutes of Health (National Cancer Institute, Frederick, USA), where she investigated the relationship between the structure and function of viral RNA. Her work also involved identifying secondary and tertiary interactions of RNA motifs that modulate viral infections. Currently, she serves as the Principal Scientist at Pfizer in the Vaccines Research and Development Department.
- Jakub Nowak, PhD
A specialist in biotechnology and molecular biology, with extensive scientific experience gained at renowned institutions such as Jagiellonian University, the University of Chicago, and the University of Edinburgh. He has worked as an application scientist, specializing in developing and supporting biophysical applications for biomolecular interactions and stability at NanoTemper Technologies. In his current research at the Małopolska Centre of Biotechnology at Jagiellonian University and within the Max Planck Research Group under the ERC project, he combines knowledge from the field of biophysics with his RNA expertise to develop innovative approaches to characterize RNA stability using state-of-the-art analytical systems.
Molecure S.A. Presenters:
- Marcin Szumowski, PhD – Chief Executive Officer, President of the Board
- Zbigniew Zasłona, PhD – Chief Scientific Officer, Board Member
- Samson Fung, PhD – Chief Medical Officer, Board Member
About Molecure
Molecure S.A. is a biotechnology company discovering and developing drugs to the clinical stage, which uses its own unique competences in the field of medicinal chemistry and biology to search for and develop first-in-class small-molecule drugs that, through direct modulation of previously unexplored protein and RNA targets, can be the therapy of many incurable diseases.
Molecure has generated a diverse portfolio of seven distinct programs with the support of leading academic scientific institutions around the world, including Yale University, Rutgers University, the Flemish Institute for Biotechnology (VIB) in Ghent, the University of Michigan, and the International Institute of Molecular and Cell Biology in Warsaw (MIBMiK).
The most advanced drug candidate developed by Molecure is OATD-01, a first-in-class CHIT1 inhibitor for use in the treatment of interstitial lung diseases such as sarcoidosis and idiopathic pulmonary fibrosis, which is ready to enter phase II clinical trials. The phase II study in patients with sarcoidosis will start in 1Q 2024 in the United States and the United Kingdom, and upon obtaining approval from regulatory authorities, it will also be continued in the European Union and Norway.
The second drug candidate is OATD-02, an oral, selective, first-in-class, dual arginase inhibitor (ARG1 and ARG2) for use in cancer treatment, whose phase I clinical trial began with its first administration to a patient in Q1 2023.
Molecure’s headquarters and laboratories are located in Warsaw and Łódź. The company is listed on the Warsaw Stock Exchange (ticker: MOC).
For more information, please visit Molecure
LinkedIn: Molecure| Twitter: @molecure_sa | YouTube: Molecure SA
For further information, please contact:
Media and individual investors:
Michał Wierzchowski, cc group
tel. +48 531 613 067
e-mail: michal.wierzchowski@ccgroup.pl
Institutional investors and sell-side analysts:
Katarzyna Mucha, cc group
tel. +48 697 613 712
e-mail: katarzyna.mucha@ccgroup.pl