Investor Overview
Molecure is a clinical stage biotechnology company that uses its world leading medicinal chemistry and biology capabilities to discover and develop first-in-class small molecule drug candidates that directly modulate the function of RNA and underexplored protein targets to treat multiple incurable diseases.
We have generated a diverse pipeline of seven distinct programs with the support of leading academic life science institutions globally, including Yale University, Rutgers University, the VIB Gent, the University of Michigan, and more recently the International Institute of Molecular and Cell Biology in Warsaw (IIMCB), which has significant expertise in RNA science.
Our most advanced in-house drug candidate is OATD-01, a first-in-class dual chitinase inhibitor for the treatment of interstitial lung diseases such as sarcoidosis and idiopathic pulmonary fibrosis that is Phase II ready. Molecure expects to start a Phase II trial in patients with sarcoidosis in 2023.
Our second proprietary candidate is OATD-02, an oral, potent and selective first-in-class, dual arginase inhibitor (ARG1 and ARG2) for the treatment of cancer, which is expected to advance to Phase I clinical development in the second half of 2022.
Our Business Model
- Our business model is based on successfully building a pipeline of small molecule drug candidates both internally and via selective in-licensing deals. We then plan to partner with global pharmaceutical and biotechnology companies for further clinical development and/or commercialization. The preferred stage of development for out-licensing is early clinical Proof of Concept.
- Our partnerships with top global academic research institutes, combined with our exceptional capabilities in medicinal chemistry and translational science, have allowed the company to access the untapped, first/best-in-class novel biology targets – both mRNA and proteins – needed to generate a pipeline of first-in-class drug candidates.
- Our approach to drug discovery is based on bold target selection, both mRNA and proteins, traditionally undrugged by small molecules, with limited competition. Drug candidates developed using this approach have attractive commercial potential and will address disease areas with significant unmet medical needs.
- Our entrepreneurial/risk taking approach allows us to successfully work on challenging, high reward targets given our preferential access to the highly regarded and rapidly growing pool of Polish top life science talent.
Investor's calendar
| DATE | EVENT |
|---|---|
| March 31, 2022 | Publication of the Company's Annual Reports for the year 2021 (separate and consolidated) |
| April 29, 2022 | Publication of the Company’s 1st quarter 2022 report |
| September 30, 2022 | Publication of the Company’s half year 2022 report |
| October 31, 2022 | Publication of the Company’s 3rd quarter 2022 report |
Stock Quotes
Shareholding Structure
Shareholders
| NUMBER OF SHARES | NOMINAL VALUE OF SHARES | SHARE IN THE SHARE CAPITAL | SHARE IN THE NUMBER OF VOTES | |
|---|---|---|---|---|
| BLACK FOREST SICAV - SIF societe anonyme | 4 135 000 | 41 350,00 | 29,47% | 29,47% |
| Szumowski Investments Sp. z o.o. | 1 010 000 | 10 100,00 | 7,20% | 7,20% |
| Marcin Szumowski | 117 163 | 1 171,63 | 0,84% | 0,84% |
| Marcin Szumowski together with Szumowski Investments Sp. z o.o. | 1 127 163 | 11 271,63 | 8,04% | 8,04% |
| Nationale-Nederlanden Universal Pension Society SA | 845 819 | 8 458,19 | 6,03% | 6,03% |
| Others | 7 922 018 | 79 220,18 | 56,46% | 56,46% |
| TOTAL | 14 030 000 | 140 300,00 | 100,00% | 100,00% |
* Members of the Management Board, Supervisory Board and shareholders of the Company do not hold any shares of BLACK FOREST SICAV-SIF societe anonyme. The indirect owner of the shares is Michał Andrzej Sołowow.
Share in capital and number of votes
Financial Information
Financial Report
ON the WSE FROM
April 19, 2018
MARKET / QUOTATION SEGMENT
WSE / Parallel
SECTOR (WSE)
Biotechnology
INDEX AFFILIATION
WIG-Poland, WIG
WSE TICKER
MOC
ISIN
PLONCTH00011
NUMBER OF SHARES ISSUED
14 030 000
Analysis
2022-11-27
Molecure aims to discover and develop drugs that have novel mechanisms of action to address serious unmet medical needs. Its two lead assets, OATD-01 and OATD-02, are approaching important clinical development milestones. After a strategic decision by partner Galapagos (June 2022), the rights to OATD-01 were returned to the company. Molecure now plans to leverage newly collected data to commence a Phase II trial in sarcoidosis in mid-2023, with top-line results expected in Q125. In addition, management anticipates OATD-02 could enter Phase I trials in solid tumour indications in Q422, subject to regulatory approval. With a cash position of PLN80.7m at end-September 2022, the company guides that its current runway is into Q224.
Research link
Go to Analyzes & Recommendations on ipopema.pl
Contact
Contact with the media and individual investors
Michał Wierzchowski
CC GROUP
+48 531 613 067 +48 531 613 067michal.wierzchowski@ccgroup.pl
Contact with institutional investors and sell-side analysts
Katarzyna Mucha
CC GROUP
+48 697 613 712 +48 22 440 1 440katarzyna.mucha@ccgroup.pl