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Category: Publications

Structure-Guided Discovery of OAT-4828 as Potent, Selective, and Orally Bioavailable USP7 Inhibitor with In Vivo Antileukemic Activity

Therapeutic inhibition of USP7 promotes antitumor immune responses

Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models

Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity

RNA-Puzzles Round V: blind predictions of 23 RNA structures

Comparative analysis of RNA 3D structure prediction methods: towards enhanced modeling of RNA-ligand interactions

Metabolism-driven glycosylation represents therapeutic opportunities in interstitial lung diseases

Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1

Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion

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Molecure is an innovative biotechnology company dedicated to discovering, developing and commercializing novel therapeutics for neoplastic and inflammatory diseases.
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